TREP, the TRansposable Elements Platform

Superfamily Penelope                   RPP

Full classification: Retrotransposon, LTR, Penelope

Penelope elements are Class 1 transposons.

They are poorly charactreised. Were found supposedly found in animals, plants, fungi and some other eukaryotes. Upon insertion, they create a variable bp Target site duplication (TSD).

Structure of Penelope elements

Sequence domains

TIR3: Terminal inverted repeat
Function: Contains motifs that are recognized and bound by the transposase. Essential for transposition.
Protein motifs:

LTR: Long terminal repeat
Function: Contains promoter and terminator elements (dual function).
Protein motifs:

RT: Reverse transcriptase
Function: Reverse transcription of mRNA to DNA, core motif is relatively variable (FY)(IAMV)DD
Protein motifs: YVDD

EN: Endonucleasease
Function:
Protein motifs:

LTR: Long terminal repeat
Function: Contains promoter and terminator elements (dual function).
Protein motifs:

0 Penelope Download all 'RPP' elements in total_TREP database elements from the following taxa are in the total_TREP database:

Taxonomic group	Total elements

---